C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event

Therapeutic targeting of specific genetic changes in cancer has proven to be an effective therapy and the concept of synthetic lethality has emerged. CCAAT/enhancer-binding protein-β (C/EBPβ), a basic leucine zipper transcription factor, has important roles in cellular processes including differenti...

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Detalles Bibliográficos
Autores principales: Messenger, Zachary J., Hall, Jonathan R., Jima, Dereje D., House, John S., Tam, Hann W., Tokarz, Debra A., Smart, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189130/
https://www.ncbi.nlm.nih.gov/pubmed/30323292
http://dx.doi.org/10.1038/s41419-018-1103-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189130/
https://www.ncbi.nlm.nih.gov/pubmed/30323292
http://dx.doi.org/10.1038/s41419-018-1103-y

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