Comparison of methods for transcriptome imputation through application to two common complex diseases

Transcriptome imputation has become a popular method for integrating genotype data with publicly available expression data to investigate the potentially causal role of genes in complex traits. Here, we compare three approaches (PrediXcan, MetaXcan and FUSION) via application to genome-wide associat...

Descripción completa

Detalles Bibliográficos
Autores principales: Fryett, James J., Inshaw, Jamie, Morris, Andrew P., Cordell, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189136/
https://www.ncbi.nlm.nih.gov/pubmed/29976976
http://dx.doi.org/10.1038/s41431-018-0176-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189136/
https://www.ncbi.nlm.nih.gov/pubmed/29976976
http://dx.doi.org/10.1038/s41431-018-0176-5

Ejemplares similares