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Comparison of methods for transcriptome imputation through application to two common complex diseases
Transcriptome imputation has become a popular method for integrating genotype data with publicly available expression data to investigate the potentially causal role of genes in complex traits. Here, we compare three approaches (PrediXcan, MetaXcan and FUSION) via application to genome-wide associat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189136/ https://www.ncbi.nlm.nih.gov/pubmed/29976976 http://dx.doi.org/10.1038/s41431-018-0176-5 |