Cargando…

Novel dihydroartemisinin derivative DHA-37 induces autophagic cell death through upregulation of HMGB1 in A549 cells

Dihydroartemisinin (DHA) and its analogs are reported to possess selective anticancer activity. Here, we reported a novel DHA derivative DHA-37 that exhibited more potent anticancer activity on the cells tested. Distinct from DHA-induced apoptosis, DHA-37 triggered excessive autophagic cell death, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xiufeng, Wu, Juanjuan, Fan, Menglin, Shen, Chen, Dai, Wenling, Bao, Yini, Liu, Ji-Hua, Yu, Bo-Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189137/ https://www.ncbi.nlm.nih.gov/pubmed/30323180 http://dx.doi.org/10.1038/s41419-018-1006-y

Ejemplares similares

Copper Oxide Nanoparticles Induce Autophagic Cell Death in A549 Cells
por: Sun, Tingting, et al.
Publicado: (2012)

Dihydroartemisinin Exerts Anti-Tumor Activity by Inducing Mitochondrion and Endoplasmic Reticulum Apoptosis and Autophagic Cell Death in Human Glioblastoma Cells
por: Qu, Chengbin, et al.
Publicado: (2017)

Derrone induces autophagic cell death through induction of ROS and ERK in A549 cells
por: Kang, Myung-Ji, et al.
Publicado: (2019)

Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells
por: Lu, Ying-Ying, et al.
Publicado: (2009)

Novel dihydroartemisinin derivative Mito-DHA(5) induces apoptosis associated with mitochondrial pathway in bladder cancer cells
por: Xiao, Linfan, et al.
Publicado: (2022)

MnSOD Upregulation Induces Autophagic Programmed Cell Death in Senescent Keratinocytes
por: Deruy, Emeric, et al.
Publicado: (2010)

The pharmaceutical death-ride of dihydroartemisinin
por: Jansen, Frans Herwig
Publicado: (2010)

DC32, a Dihydroartemisinin Derivative, Ameliorates Collagen-Induced Arthritis Through an Nrf2-p62-Keap1 Feedback Loop
por: Fan, Menglin, et al.
Publicado: (2018)

Dihydroartemisinin Reduces Irradiation-Induced Mitophagy and Radioresistance in Lung Cancer A549 Cells via CIRBP Inhibition
por: Wu, Shunlong, et al.
Publicado: (2022)

Mechanisms of Dihydroartemisinin and Dihydroartemisinin/Holotransferrin Cytotoxicity in T-Cell Lymphoma Cells
por: Wang, Qiuyan, et al.
Publicado: (2015)

Autophagic Cell Death and Cancer
por: Shimizu, Shigeomi, et al.
Publicado: (2014)

NK cell HMGB1 mediates IL-2-induced “systemic autophagic” toxicity
por: Li, Guanqiao, et al.
Publicado: (2013)

Ionizing Radiation Potentiates Dihydroartemisinin-Induced Apoptosis of A549 Cells via a Caspase-8-Dependent Pathway
por: Chen, Tongsheng, et al.
Publicado: (2013)

Salinomycin induces autophagic cell death in salinomycin-sensitive melanoma cells through inhibition of autophagic flux
por: Liu, Yajing, et al.
Publicado: (2020)

Autosis and autophagic cell death: the dark side of autophagy
por: Liu, Y, et al.
Publicado: (2015)

Chemical hybridization of sulfasalazine and dihydroartemisinin promotes brain tumor cell death
por: Ackermann, Annemarie, et al.
Publicado: (2021)

FK-16 Derived from the Anticancer Peptide LL-37 Induces Caspase-Independent Apoptosis and Autophagic Cell Death in Colon Cancer Cells
por: Ren, Shun X., et al.
Publicado: (2013)

Paclitaxel and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells
por: Klimaszewska-Wisniewska, Anna, et al.
Publicado: (2016)

Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells
por: Santoni, M, et al.
Publicado: (2013)

DHA Induces Cell Death through the Production of ROS and the Upregulation of CHOP in Fibroblast-like Synovial Cells from Human Rheumatoid Arthritis Patients
por: Jeong, Mini, et al.
Publicado: (2023)

Overcoming Basal Autophagy, Kangai Injection Enhances Cisplatin Cytotoxicity by Regulating FOXO3a-Dependent Autophagic Cell Death and Apoptosis in Human Lung Adenocarcinoma A549/DDP Cells
por: Zhou, Huan, et al.
Publicado: (2022)

Correction: FK-16 Derived from the Anticancer Peptide LL-37 Induces Caspase-Independent Apoptosis and Autophagic Cell Death in Colon Cancer Cells
por: Ren, Shun X., et al.
Publicado: (2015)

Iron Promotes Dihydroartemisinin Cytotoxicity via ROS Production and Blockade of Autophagic Flux via Lysosomal Damage in Osteosarcoma
por: Shen, Ying, et al.
Publicado: (2020)

NAC1 Modulates Sensitivity of Ovarian Cancer Cells to Cisplatin via Altering the HMGB1-Mediated Autophagic Response
por: Zhang, Yi, et al.
Publicado: (2011)

Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53-dependent pathway: Integrated bioinformatics analysis and experimental validation
por: Fan, Yameng, et al.
Publicado: (2020)

Autophagic cell death participates in POMC-induced melanoma suppression
por: Wu, Jian-Ching, et al.
Publicado: (2018)

Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response-induced upregulation of CHAC1 expression
por: Wang, Zhiwei, et al.
Publicado: (2021)

Autophagic Cell Death During Development – Ancient and Mysterious
por: Schwartz, Lawrence M.
Publicado: (2021)

DHA Hydroperoxides as a Potential Inducer of Neuronal Cell Death: a Mitochondrial Dysfunction-Mediated Pathway
por: Liu, Xuebo, et al.
Publicado: (2008)

Autophagic Upregulation Is Cytoprotective in Ischemia/Reperfusion-Injured Retina and Retinal Progenitor Cells
por: Tang, Larissa Ho Ching, et al.
Publicado: (2021)

Resistance to Dihydroartemisinin
por: Cojean, Sandrine, et al.
Publicado: (2006)

Resistance to Dihydroartemisinin
por: Legrand, Eric, et al.
Publicado: (2007)

Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells
por: Huang, Tzu-En, et al.
Publicado: (2020)

Ethanolic extract of Descurainia sophia seeds sensitizes A549 human lung cancer cells to TRAIL cytotoxicity by upregulating death receptors
por: Park, Jong-Shik, et al.
Publicado: (2016)

Autophagic Cell Death and Apoptosis Jointly Mediate Cisatracurium Besylate-Induced Cell Injury
por: Zhuang, Haixia, et al.
Publicado: (2016)

Involvement of proapoptotic genes in autophagic cell death induced by irradiation
por: Song, Jianrui, et al.
Publicado: (2017)

MG132 selectively upregulates MICB through the DNA damage response pathway in A549 cells
por: Luo, Dan, et al.
Publicado: (2019)

Clostridium difficile toxin B induces autophagic cell death in colonocytes
por: Chan, Hung, et al.
Publicado: (2018)

Iron-Dependent Autophagic Cell Death Induced by Radiation in MDA-MB-231 Breast Cancer Cells
por: Ma, Shumei, et al.
Publicado: (2021)

Autophagic flux is highly active in early mitosis and differentially regulated throughout the cell cycle
por: Li, Zhiyuan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jbk0a801k8bo3vheucur263jb1