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PHF19 promotes the proliferation, migration, and chemosensitivity of glioblastoma to doxorubicin through modulation of the SIAH1/β–catenin axis

PHD finger protein 19 (PHF19), a critical component of the polycomb repressive complex 2 (PRC2), is crucial for maintaining the repressive transcriptional activity of several developmental regulatory genes and plays essential roles in various biological processes. Abnormal expression of PHF19 causes...

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Detalles Bibliográficos
Autores principales: Deng, Qing, Hou, Jianbing, Feng, Liying, Lv, Ailing, Ke, Xiaoxue, Liang, Hanghua, Wang, Feng, Zhang, Kui, Chen, Kuijun, Cui, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189144/
https://www.ncbi.nlm.nih.gov/pubmed/30323224
http://dx.doi.org/10.1038/s41419-018-1082-z