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Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer

BACKGROUND: Human cancers can be classified based on gene signatures quantifying the degree of cell proliferation and tissue remodelling (PR). However, the specific factors that drive the increased tissue remodelling in tumours are not fully understood. Here we address this question using colorectal...

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Detalles Bibliográficos
Autores principales: Halim, Silvia, Markert, Elke K., Vazquez, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189192/
https://www.ncbi.nlm.nih.gov/pubmed/30287917
http://dx.doi.org/10.1038/s41416-018-0253-0