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Synthetic cADPR analogues may form only one of two possible conformational diastereoisomers
Cyclic adenosine 5′-diphosphate ribose (cADPR) is an emerging Ca(2+)-mobilising second messenger. cADPR analogues have been generated as chemical biology tools via both chemo-enzymatic and total synthetic routes. Both routes rely on the cyclisation of a linear precursor to close an 18-membered macro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189198/ https://www.ncbi.nlm.nih.gov/pubmed/30323284 http://dx.doi.org/10.1038/s41598-018-33484-x |