Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children’s Oncology Group

BACKGROUND: Abnormal DNA methylation may be important in germ cell tumour (GCT) aetiology, as germ cells undergo complete epigenetic reprogramming during development. GCTs show differences in global and promoter methylation patterns by histologic subtype. We conducted an epigenome-wide study to iden...

Descripción completa

Detalles Bibliográficos
Autores principales: Williams, Lindsay A., Mills, Lauren, Hooten, Anthony J., Langer, Erica, Roesler, Michelle, Frazier, A. Lindsay, Krailo, Mark, Nelson, Heather H., Bestrashniy, Jessica, Amatruda, James F., Poynter, Jenny N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189207/
https://www.ncbi.nlm.nih.gov/pubmed/30287918
http://dx.doi.org/10.1038/s41416-018-0277-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189207/
https://www.ncbi.nlm.nih.gov/pubmed/30287918
http://dx.doi.org/10.1038/s41416-018-0277-5

Ejemplares similares