Cargando…

Titin-mediated thick filament activation stabilizes myofibrils on the descending limb of their force–length relationship

PURPOSE: The aim of this study was to extend current half-sarcomere models by involving a recently found force-mediated activation of the thick filament and analyze the effect of this mechanosensing regulation on the length stability of half-sarcomeres arranged in series. METHODS: We included a supe...

Descripción completa

Detalles Bibliográficos
Autor principal: Schappacher-Tilp, Gudrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shanghai University of Sport 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189248/
https://www.ncbi.nlm.nih.gov/pubmed/30356636
http://dx.doi.org/10.1016/j.jshs.2018.05.002