Cargando…

Comparative Analysis of B-Cell Receptor Repertoires Induced by Live Yellow Fever Vaccine in Young and Middle-Age Donors

Age-related changes can significantly alter the state of adaptive immune system and often lead to attenuated response to novel pathogens and vaccination. In present study we employed 5′RACE UMI-based full length and nearly error-free immunoglobulin profiling to compare plasma cell antibody repertoir...

Descripción completa

Detalles Bibliográficos
Autores principales: Davydov, Alexey N., Obraztsova, Anna S., Lebedin, Mikhail Y., Turchaninova, Maria A., Staroverov, Dmitriy B., Merzlyak, Ekaterina M., Sharonov, George V., Kladova, Olga, Shugay, Mikhail, Britanova, Olga V., Chudakov, Dmitriy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189279/
https://www.ncbi.nlm.nih.gov/pubmed/30356675
http://dx.doi.org/10.3389/fimmu.2018.02309