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Comparative Analysis of B-Cell Receptor Repertoires Induced by Live Yellow Fever Vaccine in Young and Middle-Age Donors
Age-related changes can significantly alter the state of adaptive immune system and often lead to attenuated response to novel pathogens and vaccination. In present study we employed 5′RACE UMI-based full length and nearly error-free immunoglobulin profiling to compare plasma cell antibody repertoir...
Autores principales: | Davydov, Alexey N., Obraztsova, Anna S., Lebedin, Mikhail Y., Turchaninova, Maria A., Staroverov, Dmitriy B., Merzlyak, Ekaterina M., Sharonov, George V., Kladova, Olga, Shugay, Mikhail, Britanova, Olga V., Chudakov, Dmitriy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189279/ https://www.ncbi.nlm.nih.gov/pubmed/30356675 http://dx.doi.org/10.3389/fimmu.2018.02309 |
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