Whole-Genome Linkage Scan Combined With Exome Sequencing Identifies Novel Candidate Genes for Carotid Intima-Media Thickness

Carotid intima-media thickness (cIMT) is an established heritable marker for subclinical atherosclerosis. In this study, we aim to identify rare variants with large effects driving differences in cIMT by performing genome-wide linkage analysis of individuals in the extremes of cIMT trait distributio...

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Detalles Bibliográficos
Autores principales: Vojinovic, Dina, Kavousi, Maryam, Ghanbari, Mohsen, Brouwer, Rutger W. W., van Rooij, Jeroen G. J., van den Hout, Mirjam C. G. N., Kraaij, Robert, van Ijcken, Wilfred F. J., Uitterlinden, Andre G., van Duijn, Cornelia M., Amin, Najaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189289/
https://www.ncbi.nlm.nih.gov/pubmed/30356672
http://dx.doi.org/10.3389/fgene.2018.00420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189289/
https://www.ncbi.nlm.nih.gov/pubmed/30356672
http://dx.doi.org/10.3389/fgene.2018.00420

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