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Culture-Negative Early-Onset Neonatal Sepsis — At the Crossroad Between Efficient Sepsis Care and Antimicrobial Stewardship

Sepsis is a leading cause of mortality and morbidity in neonates. Presenting clinical symptoms are unspecific. Sensitivity and positive predictive value of biomarkers at onset of symptoms are suboptimal. Clinical suspicion therefore frequently leads to empirical antibiotic therapy in uninfected infa...

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Detalles Bibliográficos
Autores principales: Klingenberg, Claus, Kornelisse, René F., Buonocore, Giuseppe, Maier, Rolf F., Stocker, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189301/
https://www.ncbi.nlm.nih.gov/pubmed/30356671
http://dx.doi.org/10.3389/fped.2018.00285