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Defining Essentiality Score of Protein-Coding Genes and Long Noncoding RNAs

Measuring the essentiality of genes is critically important in biology and medicine. Here we proposed a computational method, GIC (Gene Importance Calculator), which can efficiently predict the essentiality of both protein-coding genes and long noncoding RNAs (lncRNAs) based on only sequence informa...

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Detalles Bibliográficos
Autores principales: Zeng, Pan, Chen, Ji, Meng, Yuhong, Zhou, Yuan, Yang, Jichun, Cui, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189311/
https://www.ncbi.nlm.nih.gov/pubmed/30356729
http://dx.doi.org/10.3389/fgene.2018.00380