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Including Phenotypic Causal Networks in Genome-Wide Association Studies Using Mixed Effects Structural Equation Models
Network based statistical models accounting for putative causal relationships among multiple phenotypes can be used to infer single-nucleotide polymorphism (SNP) effect which transmitting through a given causal path in genome-wide association studies (GWAS). In GWAS with multiple phenotypes, reconst...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189326/ https://www.ncbi.nlm.nih.gov/pubmed/30356716 http://dx.doi.org/10.3389/fgene.2018.00455 |