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17β-Estradiol Enhances Schwann Cell Differentiation via the ERβ-ERK1/2 Signaling Pathway and Promotes Remyelination in Injured Sciatic Nerves

Remyelination is critical for nerve regeneration. However, the molecular mechanism involved in remyelination is poorly understood. To explore the roles of 17β-estradiol (E2) for myelination in the peripheral nervous system, we used a co-culture model of rat dorsal root ganglion (DRG) explants and Sc...

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Detalles Bibliográficos
Autores principales: Gu, Yun, Wu, Yumen, Su, Wenfeng, Xing, LingYan, Shen, Yuntian, He, Xiaowen, Li, Lilan, Yuan, Ying, Tang, Xin, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189327/
https://www.ncbi.nlm.nih.gov/pubmed/30356713
http://dx.doi.org/10.3389/fphar.2018.01026