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17β-Estradiol Enhances Schwann Cell Differentiation via the ERβ-ERK1/2 Signaling Pathway and Promotes Remyelination in Injured Sciatic Nerves
Remyelination is critical for nerve regeneration. However, the molecular mechanism involved in remyelination is poorly understood. To explore the roles of 17β-estradiol (E2) for myelination in the peripheral nervous system, we used a co-culture model of rat dorsal root ganglion (DRG) explants and Sc...
Autores principales: | Gu, Yun, Wu, Yumen, Su, Wenfeng, Xing, LingYan, Shen, Yuntian, He, Xiaowen, Li, Lilan, Yuan, Ying, Tang, Xin, Chen, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189327/ https://www.ncbi.nlm.nih.gov/pubmed/30356713 http://dx.doi.org/10.3389/fphar.2018.01026 |
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