Olmutinib (BI1482694/HM61713), a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses ABCG2-Mediated Multidrug Resistance in Cancer Cells

The main characteristic of tumor cell resistance is multidrug resistance (MDR). MDR is the principle cause of the decline in clinical efficacy of chemotherapeutic drugs. There are several mechanisms that could cause MDR. Among these, one of the most important mechanisms underlying MDR is the overexp...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Fan, Ying-Fang, Cai, Chao-Yun, Wang, Jing-Quan, Teng, Qiu-Xu, Lei, Zi-Ning, Zeng, Leli, Gupta, Pranav, Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189370/
https://www.ncbi.nlm.nih.gov/pubmed/30356705
http://dx.doi.org/10.3389/fphar.2018.01097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189370/
https://www.ncbi.nlm.nih.gov/pubmed/30356705
http://dx.doi.org/10.3389/fphar.2018.01097

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