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Hyperphosphorylation of Tau Associates With Changes in Its Function Beyond Microtubule Stability

Tau is a neuronal microtubule associated protein whose main biological functions are to promote microtubule self-assembly by tubulin and to stabilize those already formed. Tau also plays an important role as an axonal microtubule protein. Tau is an amazing protein that plays a key role in cognitive...

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Detalles Bibliográficos
Autores principales: Alonso, Alejandra D., Cohen, Leah S., Corbo, Christopher, Morozova, Viktoriya, ElIdrissi, Abdeslem, Phillips, Greg, Kleiman, Frida E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189415/
https://www.ncbi.nlm.nih.gov/pubmed/30356756
http://dx.doi.org/10.3389/fncel.2018.00338