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Unraveling the Role of Heme in Neurodegeneration

Heme (iron-protoporphyrin IX) is an essential co-factor involved in several biological processes, including neuronal survival and differentiation. Nevertheless, an excess of free-heme promotes oxidative stress and lipid peroxidation, thus leading to cell death. The toxic properties of heme in the br...

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Detalles Bibliográficos
Autores principales: Chiabrando, Deborah, Fiorito, Veronica, Petrillo, Sara, Tolosano, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189481/
https://www.ncbi.nlm.nih.gov/pubmed/30356807
http://dx.doi.org/10.3389/fnins.2018.00712