In Vivo Persistence of Chimeric Virus after Substitution of the Kaposi's Sarcoma-Associated Herpesvirus LANA DNA Binding Domain with That of Murid Herpesvirus 4

The latency-associated nuclear antigen from Kaposi's sarcoma-associated herpesvirus (KSHV), kLANA, and its homolog from the murid herpesvirus 4 (MuHV-4), mLANA, are essential for viral latency. kLANA is nearly four times the size of mLANA, mainly due to an extensive central repeat region that i...

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Detalles Bibliográficos
Autores principales: Pires de Miranda, Marta, Quendera, Ana Patrícia, McVey, Colin E., Kaye, Kenneth M., Simas, J. Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189500/
https://www.ncbi.nlm.nih.gov/pubmed/30111565
http://dx.doi.org/10.1128/JVI.01251-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189500/
https://www.ncbi.nlm.nih.gov/pubmed/30111565
http://dx.doi.org/10.1128/JVI.01251-18

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