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Evaluation of the DREAM Technique for a High-Throughput Deorphanization of Chemosensory Receptors in Drosophila

In the vinegar fly Drosophila melanogaster, the majority of olfactory receptors mediating the detection of volatile chemicals found in their natural habitat have been functionally characterized (deorphanized) in vivo. In this process, receptors have been assigned ligands leading to either excitation...

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Detalles Bibliográficos
Autores principales: Koerte, Sarah, Keesey, Ian W., Khallaf, Mohammed A., Cortés Llorca, Lucas, Grosse-Wilde, Ewald, Hansson, Bill S., Knaden, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189519/
https://www.ncbi.nlm.nih.gov/pubmed/30356801
http://dx.doi.org/10.3389/fnmol.2018.00366