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IRS2 depletion inhibits cell proliferation and decreases hormone secretion in mouse granulosa cells

Insulin receptor substrate 2 (IRS2) is a component of the insulin/insulin-like growth factor 1 (IGF1) signaling cascade, which plays an important role in mouse hypothalamic and ovarian functions. The present study was conducted to investigate the role of IRS2 in steroidogenesis, apoptosis, cell cycl...

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Detalles Bibliográficos
Autores principales: LEI, Lanjie, HAN, Feng, CUI, Qiuyan, LIAO, Weifang, LIU, Hui, GUAN, Gaopeng, YANG, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189576/
https://www.ncbi.nlm.nih.gov/pubmed/29998910
http://dx.doi.org/10.1262/jrd.2018-055