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Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain

The human soluble Epoxide Hydrolase (hsEH) is an enzyme involved in the hydrolysis of endogenous anti-inflammatory and cardio-protective signalling mediators known as epoxyeicosatrienoic acids (EETs). EETs’ conversion into the corresponding diols by hsEH generates non-bioactive molecules, thereby th...

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Detalles Bibliográficos
Autores principales: Abis, Giancarlo, Charles, Rebecca L., Eaton, Philip, Conte, Maria R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189638/
https://www.ncbi.nlm.nih.gov/pubmed/30218745
http://dx.doi.org/10.1016/j.pep.2018.09.001