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High-Throughput Assessment of Drug Cardiac Safety Using a High-Speed Impedance Detection Technology-Based Heart-on-a-Chip

Drug cardiac safety assessments play a significant role in drug discovery. Drug-induced cardiotoxicity is one of the main reasons for drug attrition, even when antiarrhythmic drugs can otherwise effectively treat the arrhythmias. Consequently, efficient drug preclinical assessments are needed in the...

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Detalles Bibliográficos
Autores principales: Zhang, Xi, Wang, Tianxing, Wang, Ping, Hu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189730/
https://www.ncbi.nlm.nih.gov/pubmed/30404295
http://dx.doi.org/10.3390/mi7070122