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Impedance-based analysis of mu opioid receptor signaling and underlying mechanisms
The mu opioid receptor is a G-protein coupled receptor able to signal through the Gα(i)(/o) class of G-protein and β-arrestin pathways, stimulating down-stream effector pathways. Signaling bias occurs when different receptor agonists lead to different signaling outcomes. Traditionally these have bee...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189789/ https://www.ncbi.nlm.nih.gov/pubmed/30338303 http://dx.doi.org/10.1016/j.bbrep.2016.03.002 |