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Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past To Help Discover Long-Acting Oral Drugs in the Future

[Image: see text] β-Lactams represent perhaps the most important class of antibiotics yet discovered. However, despite many years of active research, none of the currently approved drugs in this class combine oral activity with long duration of action. Recent developments suggest that new β-lactam a...

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Detalles Bibliográficos
Autores principales: Smith, Paul W., Zuccotto, Fabio, Bates, Robert H., Martinez-Martinez, Maria Santos, Read, Kevin D., Peet, Caroline, Epemolu, Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189874/
https://www.ncbi.nlm.nih.gov/pubmed/30141902
http://dx.doi.org/10.1021/acsinfecdis.8b00160