Effect of a functional food (vegetable soup) on blood rheology in patients with polycythemia

OBJECTIVE: Key hemorheological variables are associated with several life-threatening diseases including cardio-cerebro-vascular diseases. A diet can influence the blood rheological variables. To compare the effectiveness of a vegetable soup on blood viscosity (BV), hematocrit (Hct), plasma fibrinogen, lipid profile, fasting blood sugar (FBS), and blood osmolarity in patients with polycythemia in comparison to a control group. MATERIALS AND METHODS: This randomized controlled trial study was conducted at Isar health clinics in Mashhad, Iran, during a 7-month period. Forty male participants (35 to 60 years old) with polycythemia, but without underlying diseases, were included. They randomly assigned to two groups and either received diet/phlebotomy or phlebotomy alone, for 6 weeks. The data were analyzed by SPSS version 16 using parametric tests. RESULTS: A significant reduction in BV at 30s (p [Formula: see text] 0.001), BV at 40s (p [Formula: see text] 0.001), BV at 50s (p [Formula: see text] 0.001), Hct (p [Formula: see text] 0.001), plasma fibrinogen (p [Formula: see text] 0.001), total cholesterol (p<0.01), LDL-cholesterol (p<0.01), VLDL-cholesterol (p [Formula: see text] 0.001), HDL-cholesterol (p [Formula: see text] 0.01), osmolarity (p [Formula: see text] 0.001), and FBS (p [Formula: see text] 0.001) was observed in diet recipients. Following the intervention, there was a significant decrease in triglyceride (intervention group, p<0.05; control group, p<0.05), in both groups. CONCLUSION: This trial showed that the plant–based food used in this study could improve blood rheology.