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Microemulsion-based hydrogels for enhancing epidermal/dermal deposition of topically administered 20(S)-protopanaxadiol: in vitro and in vivo evaluation studies

BACKGROUND: 20(S)-Protopanaxadiol (20S-PPD) is a fully deglycosylated ginsenoside metabolite and has potent dermal antiaging activity. However, because of its low aqueous solubility and large molecular size, a suitable formulation strategy is required to improve its solubility and skin permeability,...

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Detalles Bibliográficos
Autores principales: Kim, Ki-Taek, Kim, Min-Hwan, Park, Ju-Hwan, Lee, Jae-Young, Cho, Hyun-Jong, Yoon, In-Soo, Kim, Dae-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190503/
https://www.ncbi.nlm.nih.gov/pubmed/30337812
http://dx.doi.org/10.1016/j.jgr.2017.07.005