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Microemulsion-based hydrogels for enhancing epidermal/dermal deposition of topically administered 20(S)-protopanaxadiol: in vitro and in vivo evaluation studies
BACKGROUND: 20(S)-Protopanaxadiol (20S-PPD) is a fully deglycosylated ginsenoside metabolite and has potent dermal antiaging activity. However, because of its low aqueous solubility and large molecular size, a suitable formulation strategy is required to improve its solubility and skin permeability,...
Autores principales: | Kim, Ki-Taek, Kim, Min-Hwan, Park, Ju-Hwan, Lee, Jae-Young, Cho, Hyun-Jong, Yoon, In-Soo, Kim, Dae-Duk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190503/ https://www.ncbi.nlm.nih.gov/pubmed/30337812 http://dx.doi.org/10.1016/j.jgr.2017.07.005 |
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