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Therapeutic applications of genetic code expansion

In nature, a limited, conservative set of amino acids are utilized to synthesize proteins. Genetic code expansion technique reassigns codons and incorporates noncanonical amino acids (ncAAs) through orthogonal aminoacyl-tRNA synthetase (aaRS)/tRNA pairs. The past decade has witnessed the rapid growt...

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Detalles Bibliográficos
Autores principales: Huang, Yujia, Liu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190509/
https://www.ncbi.nlm.nih.gov/pubmed/30345400
http://dx.doi.org/10.1016/j.synbio.2018.09.003