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Novel vancomycin–peptide conjugate as potent antibacterial agent against vancomycin-resistant Staphylococcus aureus

BACKGROUND: Increase in vancomycin (Van)-resistant bacterial strains including vancomycin-resistant Staphylococcus aureus (VRSA) and lack of new effective antibiotics have become a formidable health problem. MATERIALS AND METHODS: We designed a new conjugate composed of Van and a peptide Hecate (Hec...

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Detalles Bibliográficos
Autores principales: Jelinkova, Pavlina, Splichal, Zbynek, Jimenez, Ana Maria Jimenez, Haddad, Yazan, Mazumdar, Aninda, Sur, Vishma Pratap, Milosavljevic, Vedran, Kopel, Pavel, Buchtelova, Hana, Guran, Roman, Zitka, Ondrej, Richtera, Lukas, Hegerova, Dagmar, Heger, Zbynek, Moulick, Amitava, Adam, Vojtech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190637/
https://www.ncbi.nlm.nih.gov/pubmed/30349337
http://dx.doi.org/10.2147/IDR.S160975