Marginal-Zone B-Cells Are Main Producers of IgM in Humans, and Are Reduced in Patients With Autoimmune Vasculitis

In mice, B1 and marginal zone (MZ) B-cells play an important role in prevention of autoimmunity through production of regulatory cytokines and natural antibodies. There is limited knowledge about the human counterparts of these cells. We therefore investigated functions of MZ-like B-cells and the fr...

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Detalles Bibliográficos
Autores principales: Appelgren, Daniel, Eriksson, Per, Ernerudh, Jan, Segelmark, Mårten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190848/
https://www.ncbi.nlm.nih.gov/pubmed/30356862
http://dx.doi.org/10.3389/fimmu.2018.02242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190848/
https://www.ncbi.nlm.nih.gov/pubmed/30356862
http://dx.doi.org/10.3389/fimmu.2018.02242

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