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Marginal-Zone B-Cells Are Main Producers of IgM in Humans, and Are Reduced in Patients With Autoimmune Vasculitis
In mice, B1 and marginal zone (MZ) B-cells play an important role in prevention of autoimmunity through production of regulatory cytokines and natural antibodies. There is limited knowledge about the human counterparts of these cells. We therefore investigated functions of MZ-like B-cells and the fr...
Autores principales: | Appelgren, Daniel, Eriksson, Per, Ernerudh, Jan, Segelmark, Mårten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190848/ https://www.ncbi.nlm.nih.gov/pubmed/30356862 http://dx.doi.org/10.3389/fimmu.2018.02242 |
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