Loss of Microglia and Impaired Brain-Neurotrophic Factor Signaling Pathway in a Comorbid Model of Chronic Pain and Depression

Major depressive disorder (MDD) and chronic pain are two complex disorders that often coexist. The underlying basis for this comorbidity is unknown. In the current investigation, microglia and the brain-derived neurotrophic factor (BDNF)-cAMP response element-binding protein (CREB) pathway were inve...

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Detalles Bibliográficos
Autores principales: Zhu, Cuizhen, Xu, Jinjie, Lin, Yezhe, Ju, Peijun, Duan, Dongxia, Luo, Yanjia, Ding, Wenhua, Huang, Shengnan, Chen, Jinghong, Cui, Donghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190863/
https://www.ncbi.nlm.nih.gov/pubmed/30356873
http://dx.doi.org/10.3389/fpsyt.2018.00442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190863/
https://www.ncbi.nlm.nih.gov/pubmed/30356873
http://dx.doi.org/10.3389/fpsyt.2018.00442

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