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Interferon-α Up-Regulates the Expression of PD-L1 Molecules on Immune Cells Through STAT3 and p38 Signaling

Interferon-α (IFNα) has one of the longest histories of use amongst cytokines in clinical oncology and has been applied for the treatment of many types of cancers. Due to its immune-activating properties, IFNα is also an attractive candidate for combinatory anti-cancer therapies. Despite its extensi...

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Detalles Bibliográficos
Autores principales: Bazhin, Alexandr V., von Ahn, Katharina, Fritz, Jasmin, Werner, Jens, Karakhanova, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190899/
https://www.ncbi.nlm.nih.gov/pubmed/30356906
http://dx.doi.org/10.3389/fimmu.2018.02129