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A Kirchhoff-Nernst-Planck framework for modeling large scale extracellular electrodiffusion surrounding morphologically detailed neurons

Many pathological conditions, such as seizures, stroke, and spreading depression, are associated with substantial changes in ion concentrations in the extracellular space (ECS) of the brain. An understanding of the mechanisms that govern ECS concentration dynamics may be a prerequisite for understan...

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Detalles Bibliográficos
Autores principales: Solbrå, Andreas, Bergersen, Aslak Wigdahl, van den Brink, Jonas, Malthe-Sørenssen, Anders, Einevoll, Gaute T., Halnes, Geir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191143/
https://www.ncbi.nlm.nih.gov/pubmed/30286073
http://dx.doi.org/10.1371/journal.pcbi.1006510