Prediction of gene regulatory enhancers across species reveals evolutionarily conserved sequence properties

Genomic regions with gene regulatory enhancer activity turnover rapidly across mammals. In contrast, gene expression patterns and transcription factor binding preferences are largely conserved between mammalian species. Based on this conservation, we hypothesized that enhancers active in different m...

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Detalles Bibliográficos
Autores principales: Chen, Ling, Fish, Alexandra E., Capra, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191148/
https://www.ncbi.nlm.nih.gov/pubmed/30286077
http://dx.doi.org/10.1371/journal.pcbi.1006484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191148/
https://www.ncbi.nlm.nih.gov/pubmed/30286077
http://dx.doi.org/10.1371/journal.pcbi.1006484

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