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Prediction of gene regulatory enhancers across species reveals evolutionarily conserved sequence properties
Genomic regions with gene regulatory enhancer activity turnover rapidly across mammals. In contrast, gene expression patterns and transcription factor binding preferences are largely conserved between mammalian species. Based on this conservation, we hypothesized that enhancers active in different m...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191148/ https://www.ncbi.nlm.nih.gov/pubmed/30286077 http://dx.doi.org/10.1371/journal.pcbi.1006484 |