A Placebo-controlled Study of PF-06473871 (Anti-Connective Tissue Growth Factor Antisense Oligonucleotide) in Reducing Hypertrophic Skin Scarring

BACKGROUND: Connective tissue growth factor (CTGF) is a matricellular protein that plays a key role in wound healing and scar formation. Inhibition of CTGF by a specific antisense oligonucleotide significantly reduced scarring and fibrosis in animal models. This study examined whether an antisense o...

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Detalles Bibliográficos
Autores principales: Gale, Jeremy D., Jensen, Jeff, Berman, Gabe, Freimuth, William, Li, Gang, Pleil, Andreas, Kutty, Malik, Rosenthal, Andrew, Boswell, C.B., Noah, V., E. Magnus, Young, Leroy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191237/
https://www.ncbi.nlm.nih.gov/pubmed/30349773
http://dx.doi.org/10.1097/GOX.0000000000001861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191237/
https://www.ncbi.nlm.nih.gov/pubmed/30349773
http://dx.doi.org/10.1097/GOX.0000000000001861

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