Mitochondrial oxidation of the carbohydrate fuel is required for neural precursor/stem cell function and postnatal cerebellar development

While deregulation of mitochondrial metabolism and cytosolic glycolysis has been well recognized in tumor cells, the role of coordinated mitochondrial oxidation and cytosolic fermentation of pyruvate, a key metabolite derived from glucose, in physiological processes is not well understood. Here, we...

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Detalles Bibliográficos
Autores principales: Zheng, Hong, Yu, Wen-Mei, Shen, Jinhua, Kang, Sumin, Hambardzumyan, Dolores, Li, James Y., Shen, Yuxian, Kenney, Anna M., Chen, Jing, Qu, Cheng-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191298/
https://www.ncbi.nlm.nih.gov/pubmed/30338292
http://dx.doi.org/10.1126/sciadv.aat2681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191298/
https://www.ncbi.nlm.nih.gov/pubmed/30338292
http://dx.doi.org/10.1126/sciadv.aat2681

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