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Mobile elements contribute to the uniqueness of human genome with 15,000 human-specific insertions and 14 Mbp sequence increase

Mobile elements (MEs) collectively contribute to at least 50% of the human genome. Due to their past incremental accumulation and ongoing DNA transposition, MEs serve as a significant source for both inter- and intra-species genetic and phenotypic diversity during primate and human evolution. By mak...

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Detalles Bibliográficos
Autores principales: Tang, Wanxiangfu, Mun, Seyoung, Joshi, Aditya, Han, Kyudong, Liang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191304/
https://www.ncbi.nlm.nih.gov/pubmed/30052927
http://dx.doi.org/10.1093/dnares/dsy022