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Cancer exosomes induce tumor innervation

Patients with densely innervated tumors suffer with increased metastasis and decreased survival as compared to those with less innervated tumors. We hypothesize that in some tumors, nerves are acquired by a tumor-induced process, called axonogenesis. Here, we use PC12 cells as an in vitro neuronal m...

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Detalles Bibliográficos
Autores principales: Madeo, Marianna, Colbert, Paul L., Vermeer, Daniel W., Lucido, Christopher T., Cain, Jacob T., Vichaya, Elisabeth G., Grossberg, Aaron J., Muirhead, DesiRae, Rickel, Alex P., Hong, Zhongkui, Zhao, Jing, Weimer, Jill M., Spanos, William C., Lee, John H., Dantzer, Robert, Vermeer, Paola D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191452/
https://www.ncbi.nlm.nih.gov/pubmed/30327461
http://dx.doi.org/10.1038/s41467-018-06640-0