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IFN-γ Producing Th1 Cells Induce Different Transcriptional Profiles in Microglia and Astrocytes

Autoreactive T cells that infiltrate into the central nervous system (CNS) are believed to have a significant role in mediating the pathology of neuroinflammatory diseases like multiple sclerosis. Their interaction with microglia and astrocytes in the CNS is crucial for the regulation of neuroinflam...

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Detalles Bibliográficos
Autores principales: Prajeeth, Chittappen K., Dittrich-Breiholz, Oliver, Talbot, Steven R., Robert, Philippe A., Huehn, Jochen, Stangel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191492/
https://www.ncbi.nlm.nih.gov/pubmed/30364000
http://dx.doi.org/10.3389/fncel.2018.00352