Cargando…

IFN-γ Producing Th1 Cells Induce Different Transcriptional Profiles in Microglia and Astrocytes

Autoreactive T cells that infiltrate into the central nervous system (CNS) are believed to have a significant role in mediating the pathology of neuroinflammatory diseases like multiple sclerosis. Their interaction with microglia and astrocytes in the CNS is crucial for the regulation of neuroinflam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prajeeth, Chittappen K., Dittrich-Breiholz, Oliver, Talbot, Steven R., Robert, Philippe A., Huehn, Jochen, Stangel, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191492/ https://www.ncbi.nlm.nih.gov/pubmed/30364000 http://dx.doi.org/10.3389/fncel.2018.00352

Ejemplares similares

Regulation of neuroinflammatory properties of glial cells by T cell effector molecules
por: Prajeeth, Chittappen K., et al.
Publicado: (2018)

Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties
por: Prajeeth, Chittappen K., et al.
Publicado: (2017)

Astrocytes Enhance Streptococcus suis-Glial Cell Interaction in Primary Astrocyte-Microglial Cell Co-Cultures
por: Seele, Jana, et al.
Publicado: (2016)

In vitro evaluation of physiologically relevant concentrations of teriflunomide on activation and proliferation of primary rodent microglia
por: Wostradowski, Tanja, et al.
Publicado: (2016)

Fumaric Acids Directly Influence Gene Expression of Neuroprotective Factors in Rodent Microglia
por: Kronenberg, Jessica, et al.
Publicado: (2019)

Fumaric Acids Do Not Directly Influence Gene Expression of Neuroprotective Factors in Highly Purified Rodent Astrocytes
por: Pars, Kaweh, et al.
Publicado: (2019)

Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis
por: Chhatbar, Chintan, et al.
Publicado: (2018)

Limited role of regulatory T cells during acute Theiler virus-induced encephalitis in resistant C57BL/6 mice
por: Prajeeth, Chittappen K, et al.
Publicado: (2014)

Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis
por: Savarin, Carine, et al.
Publicado: (2015)

Transcriptional profiling of intestinal CD4(+) T cells in the neonatal and adult mice
por: Torow, Natalia, et al.
Publicado: (2015)

Suppression of miR-155 Expression in IFN-γ-Treated Astrocytes and Microglia by DJ-1: A Possible Mechanism for Maintaining SOCS1 Expression
por: Kim, Jong-hyeon, et al.
Publicado: (2014)

IFN-γ Signaling to Astrocytes Protects from Autoimmune Mediated Neurological Disability
por: Hindinger, Claudia, et al.
Publicado: (2012)

Neuroprotection by IFN-γ via astrocyte-secreted IL-6 in acute neuroinflammation
por: Sun, Lijie, et al.
Publicado: (2017)

Identification of IFN-γ-producing innate B cells
por: Bao, Yan, et al.
Publicado: (2014)

Response Profiles of BV2 Microglia to IFN-γ and LPS Co-Stimulation and Priming
por: Pan, Meng Liy, et al.
Publicado: (2023)

LAG-3 expression in microglia regulated by IFN-γ/STAT1 pathway and metalloproteases
por: Morisaki, Yuta, et al.
Publicado: (2023)

Transient Blockade of Type I Interferon Signalling Promotes Replication of Dengue Virus Strain D2Y98P in Adult Wild-Type Mice
por: Wilken, Lucas, et al.
Publicado: (2023)

Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ
por: Lee, Jeonggi, et al.
Publicado: (2006)

Astrocyte—Microglia Interactions
por: BENVENISTE, ETTY N.
Publicado: (1993)

Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-γ Agonists
por: Gurley, Catherine, et al.
Publicado: (2008)

Differential gene expression in LPS/IFNγ activated microglia and macrophages: in vitro versus in vivo
por: Schmid, Christoph D, et al.
Publicado: (2009)

RNA-Seq transcriptomic profiling of primary murine microglia treated with LPS or LPS + IFNγ
por: Pulido-Salgado, Marta, et al.
Publicado: (2018)

IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells
por: Coomes, Stephanie M., et al.
Publicado: (2015)

IFNγ-Producing γ/δ T Cells Accumulate in the Fetal Brain Following Intrauterine Inflammation
por: Lewis, Emma L., et al.
Publicado: (2021)

Context-dependent regulation of Th17-associated genes and IFNγ expression by the transcription factor NFAT5
por: Alberdi, Maria, et al.
Publicado: (2017)

ifn-γ-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury
por: Ishii, H, et al.
Publicado: (2013)

Distinct Protein Expression Networks are Activated in Microglia Cells after Stimulation with IFN-γ and IL-4
por: Vergara, Daniele, et al.
Publicado: (2019)

LRRC25 Inhibits IFN-γ Secretion by Microglia to Negatively Regulate Anti-Tuberculosis Immunity in Mice
por: Sheng, Gang, et al.
Publicado: (2023)

Astrocytes, Microglia, and Parkinson's Disease
por: Joe, Eun-Hye, et al.
Publicado: (2018)

Astrocytes and microglia: Models and tools
por: Guttenplan, Kevin A., et al.
Publicado: (2019)

Paradoxical roles of IFN-γ in models of Th1-mediated autoimmunity
por: Rosloniec, Edward F, et al.
Publicado: (2002)

Alpha/Beta Interferon (IFN-α/β) Signaling in Astrocytes Mediates Protection against Viral Encephalomyelitis and Regulates IFN-γ-Dependent Responses
por: Hwang, Mihyun, et al.
Publicado: (2018)

IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments
por: Vardjan, Nina, et al.
Publicado: (2012)

Rift Valley Fever Virus—Infection, Pathogenesis and Host Immune Responses
por: Nair, Niranjana, et al.
Publicado: (2023)

Repression of SPI2 transcription by nitric oxide-producing, IFNγ-activated macrophages promotes maturation of Salmonella phagosomes
por: McCollister, Bruce D., et al.
Publicado: (2005)

IL-22 Is Mainly Produced by IFNγ-Secreting Cells but Is Dispensable for Host Protection against Mycobacterium tuberculosis Infection
por: Behrends, Jochen, et al.
Publicado: (2013)

IFNγ-producing CD4(+) T lymphocytes: the double-edged swords in tuberculosis
por: Kumar, Pawan
Publicado: (2017)

Recombinant Modified Vaccinia Virus Ankara Expressing a Glycosylation Mutant of Dengue Virus NS1 Induces Specific Antibody and T-Cell Responses in Mice
por: Wilken, Lucas, et al.
Publicado: (2023)

Innate IFN-γ-Producing Cells in the Spleen of Mice Early after Listeria monocytogenes Infection: Importance of Microenvironment of the Cells Involved in the Production of Innate IFN-γ
por: Kubota, Koichi, et al.
Publicado: (2011)

HIV-1 Tat Co-Operates with IFN-γ and TNF-α to Increase CXCL10 in Human Astrocytes
por: Williams, Rachel, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_uk3to6gemak3ea9mpourrm91ru