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L-Lactate Regulates the Expression of Synaptic Plasticity and Neuroprotection Genes in Cortical Neurons: A Transcriptome Analysis

Lactate, a product of aerobic glycolysis in astrocytes, is required for memory formation and consolidation, and has recently emerged as a signaling molecule for neurons and various cell types in peripheral tissues. In particular lactate stimulates mRNA expression of a few plasticity-related genes. H...

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Detalles Bibliográficos
Autores principales: Margineanu, Michael B., Mahmood, Hanan, Fiumelli, Hubert, Magistretti, Pierre J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191511/
https://www.ncbi.nlm.nih.gov/pubmed/30364173
http://dx.doi.org/10.3389/fnmol.2018.00375