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Schistosoma mansoni Egg-Released IPSE/alpha-1 Dampens Inflammatory Cytokine Responses via Basophil Interleukin (IL)-4 and IL-13

Schistosomes control inflammation in their hosts via highly effective mechanisms such as induction of Tregs, Bregs, and alternatively activated macrophages (AAMs). Notably, IPSE/alpha-1, the major secretory product from Schistosoma mansoni eggs, triggers basophils to release interleukin (IL)-4 and I...

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Detalles Bibliográficos
Autores principales: Knuhr, Katrin, Langhans, Kristina, Nyenhuis, Sandra, Viertmann, Kerstin, Kildemoes, Anna M. Overgaard, Doenhoff, Michael J., Haas, Helmut, Schramm, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191518/
https://www.ncbi.nlm.nih.gov/pubmed/30364177
http://dx.doi.org/10.3389/fimmu.2018.02293