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Mobile-Genetic-Element-Encoded Hypertolerance to Copper Protects Staphylococcus aureus from Killing by Host Phagocytes

Pathogens are exposed to toxic levels of copper during infection, and copper tolerance may be a general virulence mechanism used by bacteria to resist host defenses. In support of this, inactivation of copper exporter genes has been found to reduce the virulence of bacterial pathogens in vivo. Here...

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Detalles Bibliográficos
Autores principales: Zapotoczna, Marta, Riboldi, Gustavo P., Moustafa, Ahmed M., Dickson, Elizabeth, Narechania, Apurva, Morrissey, Julie A., Planet, Paul J., Holden, Matthew T. G., Waldron, Kevin J., Geoghegan, Joan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191537/
https://www.ncbi.nlm.nih.gov/pubmed/30327441
http://dx.doi.org/10.1128/mBio.00550-18