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Mobile-Genetic-Element-Encoded Hypertolerance to Copper Protects Staphylococcus aureus from Killing by Host Phagocytes
Pathogens are exposed to toxic levels of copper during infection, and copper tolerance may be a general virulence mechanism used by bacteria to resist host defenses. In support of this, inactivation of copper exporter genes has been found to reduce the virulence of bacterial pathogens in vivo. Here...
Autores principales: | Zapotoczna, Marta, Riboldi, Gustavo P., Moustafa, Ahmed M., Dickson, Elizabeth, Narechania, Apurva, Morrissey, Julie A., Planet, Paul J., Holden, Matthew T. G., Waldron, Kevin J., Geoghegan, Joan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191537/ https://www.ncbi.nlm.nih.gov/pubmed/30327441 http://dx.doi.org/10.1128/mBio.00550-18 |
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