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Intracellular trafficking of diphtheria toxin and its mutated form, CRM197, in the endocytic pathway
OBJECTIVE: Diphtheria toxin (DTx) is a well-characterized bacterial toxin. However, the endocytic pathway of the mutant of DTx, CRM197, which is used as an immunological adjuvant, has not yet been fully explained. The aim of this study was to investigate the intracellular trafficking of CRM197-loade...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Kare Publishing
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191554/ https://www.ncbi.nlm.nih.gov/pubmed/30374472 http://dx.doi.org/10.14744/nci.2017.55798 |